DEVELOPMENT OF OPTICAL SENSORS BASED ON SURFACE PLASMON RESONANCE (SPR) FOR HEALTH APPLICATIONS
Keywords:
optical sensor, Surface Plasmon Resonance, biomolecules, health technology, nanomaterialsAbstract
In the healthcare sector, the development of optical sensor technology has shown rapid progress, particularly through the application of the Surface Plasmon Resonance (SPR) method. SPR is an optical phenomenon that is highly sensitive to changes in the refractive index on metal surfaces, enabling real-time, non-invasive detection of biomolecules. This study aims to examine the basic principles of SPR, the main components of the sensor, and its applications in the healthcare sector through a review of the latest literature. The results of the study indicate that SPR is capable of detecting biomolecules with high sensitivity even at low concentrations, and has been successfully implemented in glucose detection via wearable sensors, identification of cancer biomarkers such as HER2 and PSA, and detection of genetic material of the SARSCoV2 virus. This technology supports efficient continuous health monitoring, but still faces challenges in cost, fabrication precision, and environmental interference. Further innovation in sensor design, microfluidic integration, and temperature compensation strategies are needed to realize accurate and affordable diagnostic systems.
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